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PMID: 851420 Published · ppublish English Journal Article

Partial amino acid sequence of rat pre-prolactin.

The Biochemical journal ·Vol. 161 ·No. 1 ·1977-01-01 ·Pages 189-92

Maurer RA, Gorski J, McKean DJ

Abstract

Rat pituitary mRNA was used to direct the cell-free synthesis of pre-prolactin labelled with [4,5-3H]leucine and either [35S] methioninc or [35S] cystine. Sequence analysis of the labelled protein indicates that pre-prolactin has 29 amino acid residues joined to the N-terminus of the prolactin sequence. Leucine residues were found at positions 13, 14, 15, 16, 21 and 22, methionine residues at positions 1, 17 and 18, and a cysteine residue at position 24 of the precursor sequence, and this partial sequence shows considerable similarity with other precursors that have been sequenced.

MeSH Terms
Amino Acid Sequence Animals Prolactin/analysis Rats
Chemicals
Prolactin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Maurer R A
Gorski J
McKean D J
References (20)
20 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj1610189
Published
1977-01-01
Pages
189-92
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1164489
Subset
IM
External Links
PubMed source DOI: 10.1042/bj1610189 PMC Full Text View journal details
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