Dried-blood spot screening for cystic fibrosis in the newborn.

Lancet (London, England) ·Vol. 1 ·No. 8114 ·1979-03-03 ·Pages 472-4

Crossley JR, Elliott RB, Smith PA

Abstract

Serum-immunoreactive-trypsin (I.R.T.) was measured in children with cystic fibrosis (C.F.) and a variety of controls. In the first few months of life all C.F. children had a raised serum-I.R.T. A dried blood-spot assay for I.R.T. was established and has potential as a screening test for C.F. in the newborn.

MeSH Terms

Antigens Blood Specimen Collection Blood Stains Cystic Fibrosis/diagnosis,enzymology Humans Infant Infant, Newborn Radioimmunoassay Trypsin/blood,immunology

Chemicals

Antigens Trypsin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Crossley J R

Elliott R B

Smith P A

Article Info

Journal

Lancet (London, England)

Abbr.

Lancet

ISSN

0140-6736

DOI

10.1016/s0140-6736(79)90825-0

Published

1979-03-03

Pages

472-4

Language

English

Region

England

NLM ID

2985213R

Subset

External Links

PubMed source DOI: 10.1016/s0140-6736(79)90825-0 View journal details

Analysis Services

Dried-blood spot screening for cystic fibrosis in the newborn.

Contact

WeChat Official Account