In vitro interaction between cyclosporin A and macrolide antibiotics.

British journal of clinical pharmacology ·Vol. 35 ·No. 4 ·1993-04-00 ·Pages 447-8

Marre F, de Sousa G, Orloff AM, Rahmani R

Abstract

暂无摘要

MeSH Terms

Anti-Bacterial Agents/pharmacology Cyclosporine/metabolism,pharmacology Drug Interactions Humans In Vitro Techniques Microsomes, Liver/drug effects,metabolism Miocamycin/analogs & derivatives,pharmacology Oxidation-Reduction

Chemicals

Anti-Bacterial Agents Miocamycin Cyclosporine rokitamycin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Marre F

de Sousa G

Orloff A M

Rahmani R

References (11)

11 references, click to expand

Effect of erythromycin on cyclosporine levels.
N Engl J Med. 1985 Nov 28;313(22):1416-7 PMID: 4058537
Possible interaction between cyclosporine and erythromycin.
N Engl J Med. 1986 Feb 13;314(7):448 PMID: 3511381
Effect of josamycin on plasma cyclosporine levels.
Eur J Clin Pharmacol. 1987;32(3):327-8 PMID: 3595708
Metabolism of cyclosporin A. I. Study in freshly isolated rabbit hepatocytes.
Drug Metab Dispos. 1987 May-Jun;15(3):384-90 PMID: 2886316
In vivo and in vitro effects of a new macrolide antibiotic roxithromycin on rat liver cytochrome P-450: comparison with troleandomycin and erythromycin.
Chem Biol Interact. 1988;68(3-4):179-88 PMID: 3265076
Use of human and animal liver microsomes in drug metabolic studies.
Eur J Drug Metab Pharmacokinet. 1991;Spec No 3:458-65 PMID: 1820923
Lack of effect of spiramycin on cyclosporin pharmacokinetics.
Br J Clin Pharmacol. 1989 Jun;27(6):789-94 PMID: 2667601
Interaction between roxithromycin and cyclosporin in heart transplant patients.
Clin Pharmacokinet. 1990 Dec;19(6):499-502 PMID: 2292171
Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
Drug Metab Dispos. 1990 Sep-Oct;18(5):595-606 PMID: 1981707
Involvement of the cytochrome P-450IID subfamily in minaprine 4-hydroxylation by human hepatic microsomes.
Drug Metab Dispos. 1992 Mar-Apr;20(2):316-21 PMID: 1352227
Metabolism of cyclosporin A. IV. Purification and identification of the rifampicin-inducible human liver cytochrome P-450 (cyclosporin A oxidase) as a product of P450IIIA gene subfamily.
Drug Metab Dispos. 1989 Mar-Apr;17(2):197-207 PMID: 2565211

Article Info

Journal

British journal of clinical pharmacology

Abbr.

Br J Clin Pharmacol

ISSN

0306-5251

DOI

10.1111/j.1365-2125.1993.tb04166.x

Published

1993-04-00

Pages

447-8

Language

English

Region

England

NLM ID

7503323

PMCID

PMC1381560

Subset

External Links

PubMed source DOI: 10.1111/j.1365-2125.1993.tb04166.x PMC Full Text View journal details

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In vitro interaction between cyclosporin A and macrolide antibiotics.

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