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PMID: 84718 Published · ppublish fre English Abstract Journal Article

[Antigenic determinants of beta-LPH, beta-MSH, alpha-endorphin, ACTH and alpha-MSH revealed by anti-beta-endorphin in neurons of the human infundibular nucleus].

Présence de déterminants antigéniques de la beta-LPH, de la beta-MSH, de l'alpha-endorphine, de l'ACTH et de l'alpha-MSH dans les neurones révélés par l'anti-beta-endorphine au niveau du noyau infundibulaire de l'Homme.

Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles ·Vol. 287 ·No. 11 ·1978-10-30 ·Pages 1019-22

Bloch B, Bugnon C, Fellmann D, Lenys D

Abstract

Comparison of adjacent serial sections of the tubero-infundibular region of Human adult hypothalamus demonstrates that the same perikarya, axons and terminals are stained both with anti-beta-endorphin and anti 17-39 ACTH antisera. The most immunoreactive of these neurons are also revealed with anti alpha-endorphin, anti alpha and beta-MSH, anti-1-24 ACTH and anti beta-LPH. These results suggest that neurons of the infundibular nucleus can store and probably secrete peptide similar to propiocortin or fragment(s) of this molecule.

MeSH Terms
Adrenocorticotropic Hormone/immunology Adult Endorphins/immunology Epitopes Humans Hypothalamus/immunology Melanocyte-Stimulating Hormones/immunology Neurons/immunology beta-Lipotropin/immunology
Chemicals
Endorphins Epitopes Adrenocorticotropic Hormone Melanocyte-Stimulating Hormones beta-Lipotropin
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Bloch B
Bugnon C
Fellmann D
Lenys D
Article Info
Journal
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles
Abbr.
C R Acad Hebd Seances Acad Sci D
Published
1978-10-30
Pages
1019-22
Language
fre
Region
France
NLM ID
7501107
Subset
IM
External Links
PubMed source
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