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PMID: 8471191 Published · ppublish English Comparative Study Editorial Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Biology of Toxoplasma gondii.

AIDS (London, England) ·Vol. 7 ·No. 3 ·1993-03-00 ·Pages 299-316

Wong SY, Remington JS

Abstract

In conclusion, a large body of new information on the biology and immunology of T. gondii has accumulated in the past several years. Much of this is due to the advent of AIDS and the increased funding made available to researchers interested in opportunistic infections in this patient population. These scientific advances have led to a better understanding of the process by which Toxoplasma infects mammalian host cells, molecular biology and biochemistry of the parasite, antigenic structure and immune response to the infection and approaches to be adopted for drug design and therapeutic strategies. Thus, it is through such recognition of the importance of understanding the basic science of an opportunistic pathogen that such advances can be realized.

MeSH Terms
AIDS-Related Opportunistic Infections/complications,immunology,parasitology,therapy Animals Antiprotozoal Agents/therapeutic use Cats Cricetinae DNA, Protozoan/analysis Host-Parasite Interactions Humans Immunologic Factors/therapeutic use Mice Oxidation-Reduction Polymerase Chain Reaction Protozoan Proteins/immunology Rabbits Rats Toxoplasma/classification,growth & development,isolation & purification,pathogenicity,physiology Toxoplasmosis/complications,immunology,parasitology,therapy Toxoplasmosis, Animal/parasitology Virulence
Chemicals
Antiprotozoal Agents DNA, Protozoan Immunologic Factors Protozoan Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wong S Y
Remington J S
Article Info
Journal
AIDS (London, England)
Abbr.
AIDS
ISSN
0269-9370
Published
1993-03-00
Pages
299-316
Language
English
Region
England
NLM ID
8710219
Subset
IM
Grants
NIAID NIH HHS · AI04717 · United States
NIAID NIH HHS · AI30320 · United States
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