Pharmacokinetic and biopharmaceutic profile of chlordiazepoxide HC1 in healthy subjects: multiple-dose oral administration.

Journal of pharmacokinetics and biopharmaceutics ·Vol. 5 ·No. 1 ·1977-02-00 ·Pages 25-39

Boxenbaum HG, Geitner KA, Jack ML, Dixon WR, Kaplan SA

Abstract

暂无摘要

MeSH Terms

Administration, Oral Adult Biopharmaceutics Chlordiazepoxide/administration & dosage,metabolism Humans Kinetics Male

Chemicals

Chlordiazepoxide

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Boxenbaum H G

Geitner K A

Jack M L

Dixon W R

Kaplan S A

References (10)

10 references, click to expand

Hepatic vascular bed.
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Pharmacology of the metabolites of chlordiazepoxide and diazepam.
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Pharmacokinetic and biopharmaceutic profile of chlordiazepoxide HC1 in healthy subjects: single-dose studies by the intravenous, intramuscular, and oral routes.
J Pharmacokinet Biopharm. 1977 Feb;5(1):3-23 PMID: 845790
N-desmethyldiazepam: a new metabolite of chlordiazepoxide in man.
Clin Pharmacol Ther. 1976 Oct;20(4):450-7 PMID: 788991
General treatment of linear mammillary models with elimination from any compartment as used in pharmacokinetics.
J Pharm Sci. 1972 Apr;61(4):536-41 PMID: 5014309
Pharmacokinetic model for chlordiazepoxide--HCl in the dog.
J Pharm Sci. 1970 Nov;59(11):1569-74 PMID: 5495479
Intrasubject variation in elimination half-lives of drugs which are appreciably metabolized.
J Pharmacokinet Biopharm. 1973 Apr;1(2):165-73 PMID: 4797185
Statistical estimations in pharmacokinetics.
J Pharmacokinet Biopharm. 1974 Apr;2(2):123-48 PMID: 4427218
Do you need a pharmacokinetic model, and, if so, which one?
J Pharmacokinet Biopharm. 1975 Dec;3(6):457-78 PMID: 1206481
Concept of a volume of distribution and possible errors in evaluation of this parameter.
J Pharm Sci. 1968 Jan;57(1):128-33 PMID: 5652112

Article Info

Journal

Journal of pharmacokinetics and biopharmaceutics

Abbr.

J Pharmacokinet Biopharm

ISSN

0090-466X

DOI

Published

1977-02-00

Pages

25-39

Language

English

Region

United States

NLM ID

0357115

Subset

External Links

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