The N-terminal sequences of two calf-thymus non-histone chromosomal proteins, HMG-1 and HMG-2, are compared. Both N-terminal sequences are basic, and differ at only one position. This contrasts with the C-terminal portion of HMG-1 which we have previously shown to be high in acidic residues. There is no obvious sequence homology with any of the known sequences of the histones.
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