Unravelling the tangled web at the microtubule-organizing center.

Current opinion in cell biology ·Vol. 5 ·No. 1 ·1993-02-00 ·Pages 105-15

Rose MD, Biggins S, Satterwhite LL

Abstract

The last year has seen dramatic progress in the use of genetic and biochemical approaches to identify microtubule-organizing center components. The use of vertebrate and invertebrate egg extracts has allowed the development of novel assays for centrosome duplication and activation. A variety of mutations in fungi are being used to sort out the pathway of spindle pole body duplication.

Related Genes

MeSH Terms

Animals Cell Division Cyclins/metabolism Eukaryotic Cells/ultrastructure Fungal Proteins/genetics,metabolism Fungi/genetics,ultrastructure Invertebrates/genetics,metabolism Microtubule Proteins/genetics,metabolism Microtubules/ultrastructure Mitosis Phosphorylation Protein Processing, Post-Translational Spindle Apparatus/ultrastructure

Chemicals

Cyclins Fungal Proteins Microtubule Proteins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Rose M D

Department of Molecular Biology, Princeton University, New Jersey 08455-1014.

Biggins S

Satterwhite L L

Article Info

Journal

Current opinion in cell biology

Abbr.

Curr Opin Cell Biol

ISSN

0955-0674

DOI

10.1016/s0955-0674(05)80015-8

Published

1993-02-00

Pages

105-15

Language

English

Region

England

NLM ID

8913428

Subset

Grants

NIGMS NIH HHS · R01 GM037739 · United States

External Links

PubMed source DOI: 10.1016/s0955-0674(05)80015-8 View journal details

Analysis Services

Unravelling the tangled web at the microtubule-organizing center.

Contact

WeChat Official Account