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PMID: 8388512 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Human foamy virus polypeptides: identification of env and bel gene products.

Journal of virology ·Vol. 67 ·No. 6 ·1993-06-00 ·Pages 3596-600

Giron ML, Rozain F, Debons-Guillemin MC, Canivet M, Peries J, Emanoil-Ravier R

Abstract

Human foamy virus (HFV) proteins were identified in human cells cultured in vitro by immunoprecipitation and immunoblotting with specific antisera. Among several viral polypeptides, four glycoproteins of approximately 160, 130, 70, and 48 kDa were identified in HFV-infected cells. gp130 was shown to represent the intracellular env precursor, and gp70 and gp48 were shown to represent the external and transmembrane env proteins, respectively. The nature of gp160, which shares sequences with the env, bel1, and bel2 proteins, is not yet resolved. In addition, a p62 identified with bel1- and bel2-specific antisera likely corresponds to the bet gene product.

Related Genes
bel1 bel2 env
MeSH Terms
Antibodies, Viral Blotting, Western Cells, Cultured DNA-Binding Proteins/isolation & purification Gene Products, env/isolation & purification Genes, Viral Humans Retroviridae Proteins/isolation & purification Spumavirus/chemistry Trans-Activators/isolation & purification
Chemicals
Antibodies, Viral DNA-Binding Proteins Gene Products, env Retroviridae Proteins Trans-Activators bel1 protein, Human foamy virus
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Giron M L
UPR A0043 CNRS Rétrovirus et Rétrotransposons des Vertébrés, Hôpital Saint-Louis, Paris, France.
Rozain F
Debons-Guillemin M C
Canivet M
Peries J
Emanoil-Ravier R
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.67.6.3596-3600.1993
Published
1993-06-00
Pages
3596-600
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC237707
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.67.6.3596-3600.1993 PMC Full Text View journal details
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