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PMID: 8383668 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The unstable melC operon of Streptomyces antibioticus is codeleted with a Tn4811-homologous locus.

Journal of bacteriology ·Vol. 175 ·No. 6 ·1993-03-00 ·Pages 1847-52

Yu TW, Chen CW

Abstract

The melC operon of Streptomyces antibioticus is unstable, undergoing frequent spontaneous deletions. All the delta melC mutants analyzed also lost 2-kb V1 DNA, which contained two open reading frames (ORFs) homologous to ORF4 (a putative oxidoreductase gene) and ORF5 (a putative AraC-type regulatory gene) of Tn4811. The two ORFs may constitute an accessory unit of a different transposon.

Related Genes
melC
MeSH Terms
Amino Acid Sequence Base Sequence DNA Transposable Elements DNA, Bacterial Gene Amplification Melanins/genetics Molecular Sequence Data Operon Restriction Mapping Sequence Deletion Streptomyces antibioticus/genetics
Chemicals
DNA Transposable Elements DNA, Bacterial Melanins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Yu T W
Institute of Genetics, National Yang-Ming Medical College, Taipei, Taiwan, Republic of China.
Chen C W
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24 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.175.6.1847-1852.1993
Published
1993-03-00
Pages
1847-52
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC203993
Subset
IM
Databases
GENBANK
M96551
External Links
PubMed source DOI: 10.1128/jb.175.6.1847-1852.1993 PMC Full Text View journal details
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