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题目:: [Change in levels of specific terminal sugar residues of glycoproteins in sera of patients with malignant tumor].
作者:: Nishida(K),Nagamura(Y),Ohta(Y),Ito(M),Ishiguro(I)
状态:: 发布时间1993-10-12 , 更新时间 2015-11-19
期刊:: Rinsho Byori
摘要:: Serum sialic acid (N-acetylneuraminic acid, NANA) levels significantly increased in all of patients with stomach cancer, colo-rectal cancer, breast cancer and pancreas cancer. However, the positive rate for serum NANA levels was 35 approximately 60% in these diseases. In contrast, a significant increase in serum NANA-galactose (NANA-Gal) levels was found in only stomach cancer and colo-rectal cancer; especially, the positive rate for serum NANA-Gal levels was 77% in colo-rectal cancer. In colo-rectal cancer, increased serum NANA-Gal levels were decreased after operation. But, in patients with colo-rectal cancer, changes in serum NANA levels following operation were variable. These results indicate that the assay of serum NANA-Gal level provides more important clinical significances for the specificity of cancer and the change of its status than that of serum NANA level.
语言:: jpn
DOI:

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