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PMID: 8328913 Published · ppublish English Journal Article

Sequence analysis of the PrP protein from two species of antelope susceptible to transmissible spongiform encephalopathy.

Archives of virology ·Vol. 131 ·No. 1-2 ·1993-00-00 ·Pages 193-9

Poidinger M, Kirkwood J, Almond W

Abstract

The sequence of the coding regions of the PrP genes of the Arabian oryx and greater kudu have been determined and compared with the related sheep and bovine PrP gene sequences. The oryx gene sequence was found to be very closely related to that of the sheep, encoding just one amino acid difference. The greater kudu gene sequence was found to be more closely related to the bovine, encoding four amino acid differences. The possible influence that the gene sequences have on the transmission of spongiform encephalopathy to these antelope species is discussed.

Related Genes
PrP
MeSH Terms
Animals Antelopes/genetics Base Sequence Cattle DNA Genetic Predisposition to Disease Molecular Sequence Data Prion Diseases/immunology,microbiology,veterinary Prions/genetics Sheep
Chemicals
Prions DNA
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Poidinger M
Department of Microbiology, School of Animal and Microbial Sciences, University of Reading, U.K.
Kirkwood J
Almond W
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26 references, click to expand
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Article Info
Journal
Archives of virology
Abbr.
Arch Virol
ISSN
0304-8608
DOI
10.1007/BF01379091
Published
1993-00-00
Pages
193-9
Language
English
Region
Austria
NLM ID
7506870
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01379091 View journal details
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