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题目:: Monoclonal antibodies directed against surface and intracellular antigens of mouse granulated metrial gland cells.
作者:: Stewart(I J),Mukhtar(D D),Sawyer(A M),Wild(A E)
状态:: 发布时间1994-07-08 , 更新时间 2009-09-29
期刊:: J Immunol Methods
摘要:: Rat monoclonal antibodies with reactivity directed against mouse GMG cells have been produced. One of the antibodies (GMG-1) reacts with a surface antigen of GMG cells and cross-reacts with T lymphocytes. Another (GMG-2) reacts with an intracellular antigen in GMG cells and with asialo-GM1 positive cells in the spleen. Three antibodies (GMG-3, -4, -5) bind to intracellular antigens in GMG cells. The cross-reactivity of these antibodies is discussed with reference to the lineage relationship of GMG cells to NK cells and T cells and the recent suggestion that NK cells and T cells have a common progenitor cell. It is proposed that GMG cells share this common progenitor cell but are otherwise independent of the NK or T cell lineages.
语言:: eng
DOI:

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