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PMID: 8156275 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Short-sighted evolution and the virulence of pathogenic microorganisms.

Trends in microbiology ·Vol. 2 ·No. 3 ·1994-03-00 ·Pages 76-81

Levin BR, Bull JJ

Abstract

For some microorganisms, virulence may be an inadvertent consequence of mutation and selection in the parasite population, occurring within a host during the course of an infection. This type of virulence is short-sighted, in that it engenders no advantage to the pathogen beyond the afflicted host. Bacterial meningitis, poliomyelitis and AIDS are three candidates for this model of the evolution of virulence.

MeSH Terms
Acquired Immunodeficiency Syndrome/microbiology Bacteria/pathogenicity Biological Evolution HIV/pathogenicity Humans Meningitis, Bacterial/microbiology Mutation Poliomyelitis/microbiology Poliovirus/pathogenicity Virulence
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Levin B R
Dept of Biology, Emory University, Atlanta, GA 30322.
Bull J J
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
Published
1994-03-00
Pages
76-81
Language
English
Region
England
NLM ID
9310916
Subset
IM
Grants
NIGMS NIH HHS · GM33782 · United States
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