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PMID: 8143112 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

The wily ways of a parasite: induction of actin assembly by Listeria.

Trends in microbiology ·Vol. 1 ·No. 1 ·1993-04-00 ·Pages 25-31

Tilney LG, Tilney MS

Abstract

The intracellular pathogen Listeria has a spectacular mode of transport within and between host cells. By inducing host cell actin to assemble from its surface, the bacterium forms a tail composed of many short, crossbridged actin filaments. With this tail Listeria is propelled across the cytoplasm like a comet streaking across the sky. Here we discuss the antics of Listeria and some of the bacterial genes instrumental in maintaining it in the host.

MeSH Terms
Actins/metabolism Genes, Bacterial/physiology Listeria/genetics,metabolism,pathogenicity Macrophages/microbiology
Chemicals
Actins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tilney L G
Dept of Biology, University of Pennsylvania, Philadelphia 19104-6018.
Tilney M S
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
Published
1993-04-00
Pages
25-31
Language
English
Region
England
NLM ID
9310916
Subset
IM
Grants
NICHD NIH HHS · HD 14474 · United States
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