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题目:: The functions of antigen recognition in T cell-dependent B cell activation.
作者:: Parker(D C)
状态:: 发布时间1994-04-12 , 更新时间 2007-11-14
期刊:: Semin Immunol
摘要:: B cells get help from T cells by acting as antigen-specific APC. A signal from the B cell antigen receptor is not required for efficient antigen presentation or for the B cell response to T cell help. T cells provide help by making lymphokines, some of which, like CD40 ligand, remain T cell-associated and require cell contact for function. The function of class II MHC is to induce help in the T cell, rather than to deliver help to the B cell. T cell help uses different intracellular signaling pathways from those engaged by the B cell antigen receptor.
语言:: eng
DOI:: 10.1006/smim.1993.1047

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