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PMID: 8123784 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

MAP kinases: universal multi-purpose signaling tools.

Plant molecular biology ·Vol. 24 ·No. 3 ·1994-02-00 ·Pages 407-16

Jonak C, Heberle-Bors E, Hirt H

Abstract

MAP (mitogen-activated protein) kinases are serine/threonine protein kinases and mediate intracellular phosphorylation events linking various extracellular signals to different cellular targets. MAP kinase, MAP kinase kinase and MAP kinase kinase kinase are functional protein kinase units that are conserved in several signal transduction pathways in animals and yeasts. Isolation of all three components was also shown in plants and suggests conservation of a protein kinase module in all eukaryotic cells. In plants, MAP kinase modules appear to be involved in ethylene signaling and auxin-induced cell proliferation. Therefore, coupling of different extracellular signals to different physiological responses is mediated by MAP kinase cascades and appears to have evolved from a single prototypical protein kinase module which has been adapted to the specific requirements of different organisms.

MeSH Terms
Animals Calcium-Calmodulin-Dependent Protein Kinases/metabolism Humans Plant Physiological Phenomena Plants/enzymology Saccharomyces cerevisiae/enzymology,physiology Schizosaccharomyces/enzymology,physiology Signal Transduction Vertebrates
Chemicals
Calcium-Calmodulin-Dependent Protein Kinases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Jonak C
Institute of Microbiology and Genetics, University of Vienna, Austria.
Heberle-Bors E
Hirt H
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Article Info
Journal
Plant molecular biology
Abbr.
Plant Mol Biol
ISSN
0167-4412
DOI
10.1007/BF00024109
Published
1994-02-00
Pages
407-16
Language
English
Region
Netherlands
NLM ID
9106343
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00024109 View journal details
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