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PMID: 808131 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation).

American journal of ophthalmology ·Vol. 80 ·No. 1 ·1975-07-00 ·Pages 1-23

Machemer R, Laqua H

Abstract

Cell proliferation and membrane formation found in the posterior parts of the eye after production of retinal detachment in owl monkey eyes had either the characteristics of macrophages or of membrane-forming epithelial cells. The proliferating cells originated from pigment epithelium. These membranes caused folding of the retina and strand formation in the vitreous cavity. Since cell proliferation was present on all available surfaces, such as the upper and under surface of the retina, and along vitreous surfaces, we propose to call this entity "massive periretinal proliferation" (MPP).

MeSH Terms
Animals Autoradiography Cell Division DNA/biosynthesis Disease Models, Animal Epithelial Cells Epithelium/pathology,ultrastructure Fibroblasts/pathology,ultrastructure Haplorhini Macrophages/pathology,ultrastructure Membranes Microscopy, Electron Retina/pathology Retinal Detachment/pathology Thymidine/metabolism Vitreous Body/pathology
Chemicals
DNA Thymidine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Machemer R
Laqua H
Article Info
Journal
American journal of ophthalmology
Abbr.
Am J Ophthalmol
ISSN
0002-9394
Published
1975-07-00
Pages
1-23
Language
English
Region
United States
NLM ID
0370500
Subset
IM
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