The major cause of inactivation and mutation by 4-nitroquinoline 1-oixde in Escherichia coli: excisable 4NQO-purine adducts.

4-Nitroquinoline-1-oxide/pharmacology DNA Repair/drug effects DNA Replication/drug effects DNA, Bacterial/metabolism,radiation effects Escherichia coli/drug effects,metabolism,radiation effects Mutagens Mutation Nitroquinolines/pharmacology Purines/metabolism Radiation Genetics Species Specificity Time Factors Ultraviolet Rays

DNA, Bacterial Mutagens Nitroquinolines Purines 4-Nitroquinoline-1-oxide