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PMID: 806259 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

RPL11, an R factor of Pseudomonas aeruginosa determining carbenicillin and gentamicin resistance.

Antimicrobial agents and chemotherapy ·Vol. 7 ·No. 1 ·1975-01-00 ·Pages 69-73

Korfhagen TR, Loper JC

Abstract

R factor RPL11 from Pseudomonas aeruginosa determines multiple drug resistance including resistance to gentamicin and carbenicillin. The host range and incompatibility properties of RPL11 are those of incompatibility group P-2. Strains harboring the factor are not altered with respect to the major immunotypes 1 through 7 of Parke-Davis, or with respect to pyocin type by using the 18 indicators of Jones and co-workers. Analytical ultracentrifugation of crude extracts of R factor-containing strains shows a band of satellite DNA with a buoyant density of 1.717 g/cm(3).

MeSH Terms
Carbenicillin/pharmacology Extrachromosomal Inheritance Gentamicins/pharmacology Penicillin Resistance Pseudomonas aeruginosa/drug effects
Chemicals
Gentamicins Carbenicillin
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Korfhagen T R
Loper J C
References (18)
18 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.7.1.69
Published
1975-01-00
Pages
69-73
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC429075
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.7.1.69 PMC Full Text View journal details
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