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PMID: 804353 Published · ppublish English Comparative Study Journal Article

Cell number and cell density in the cerebellar cortex of man and some other mammals.

Cell and tissue research ·Vol. 157 ·No. 1 ·1975-00-00 ·Pages 115-24

Lange W

Abstract

The number of cells per unit volume was determined in the cerebellar cortex of man and 19 other mammals. The cell density (i.e. the number of cells per unit volume) decreases from mammals with a low brain weight to those with a higher brain weight. This decrease in the number of cells is found to be proportional for all three layers of the cerebellar cortex. In addition, the ratio of Purkinje cells to granule cells was determined. In contrast to the decrease of all cell types with increasing brain weight, this ratio varies remarkably among the mammals and is not correlated with brain weight. In man, this ratio is 1:2991, while it is lower in all other mammals investigated. These differences in the ratio of Purkinje cells to granule cells and the decrease in cell density with increasing brain weight are discussed in relation to brain evolution.

MeSH Terms
Animals Artiodactyla/anatomy & histology Biological Evolution Carnivora/anatomy & histology Cell Count Cerebellar Cortex/cytology Cetacea/anatomy & histology Elephants/anatomy & histology Eulipotyphla/anatomy & histology Haplorhini/anatomy & histology Humans Mammals/anatomy & histology Opossums/anatomy & histology Organ Size Purkinje Cells/cytology Rabbits/anatomy & histology Rodentia/anatomy & histology Species Specificity
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Lange W
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20 references, click to expand
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Article Info
Journal
Cell and tissue research
Abbr.
Cell Tissue Res
ISSN
0302-766X
DOI
10.1007/BF00223234
Published
1975-00-00
Pages
115-24
Language
English
Region
Germany
NLM ID
0417625
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00223234 View journal details
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