The SMS1 gene encoding a serine-rich transmembrane protein suppresses the temperature sensitivity of the htr1 disruptant in Saccharomyces cerevisiae.

Biochimica et biophysica acta ·Vol. 1260 ·No. 1 ·1995-01-02 ·Pages 94-6

Takeuchi J, Okada M, Toh-e A, Kikuchi Y

Abstract

A new gene (SMS1; serine-rich multi-copy suppressor) of Saccharomyces cerevisiae was isolated by the ability to suppress the temperature sensitivity of the htr1 disruptant (Kikuchi et al. (1994) Mol. Gen. Genetics, in press) by increasing its gene dosage. The predicted gene product contains a serine-rich domain followed by a putative transmembrane region. The SMS1 gene was physically and genetically mapped in the region near cdc3 on chromosome XII R.

Related Genes

HTR1 SMS1

MeSH Terms

Amino Acid Sequence Base Sequence Chromosome Mapping Chromosomes, Fungal DNA, Fungal Fungal Proteins/genetics Gene Dosage Membrane Transport Proteins Mitochondrial Membrane Transport Proteins Mitochondrial Precursor Protein Import Complex Proteins Molecular Sequence Data Repressor Proteins/genetics Saccharomyces cerevisiae/genetics Saccharomyces cerevisiae Proteins Suppression, Genetic Temperature

Chemicals

DNA, Fungal Fungal Proteins Membrane Transport Proteins Mitochondrial Membrane Transport Proteins Mitochondrial Precursor Protein Import Complex Proteins Repressor Proteins Saccharomyces cerevisiae Proteins TIM17 protein, S cerevisiae

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Takeuchi J

Department of Plant Sciences, Graduate School of Science, University of Tokyo, Japan.

Okada M

Toh-e A

Kikuchi Y

Article Info

Journal

Biochimica et biophysica acta

Abbr.

Biochim Biophys Acta

ISSN

0006-3002

DOI

10.1016/0167-4781(94)00188-9

Published

1995-01-02

Pages

94-6

Language

English

Region

Netherlands

NLM ID

0217513

Subset

Databases

GENBANK

D29964

External Links

PubMed source DOI: 10.1016/0167-4781(94)00188-9

Analysis Services

The SMS1 gene encoding a serine-rich transmembrane protein suppresses the temperature sensitivity of the htr1 disruptant in Saccharomyces cerevisiae.

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