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PMID: 7953521 Published · ppublish English Journal Article Review

Autoimmune disease. Gadding around the beta cell.

Current biology : CB ·Vol. 4 ·No. 2 ·1994-02-01 ·Pages 158-60

Cooke A

Abstract

Recent studies shed new light on the process by which T-cell tolerance to pancreatic beta-cell antigens breaks down, leading to the autoimmune disease insulin-dependent diabetes mellitus.

MeSH Terms
Animals Autoimmune Diseases/immunology CD4-Positive T-Lymphocytes/immunology CD8-Positive T-Lymphocytes/immunology Diabetes Mellitus, Type 1/immunology Glutamate Decarboxylase/genetics Humans Islets of Langerhans/immunology Macrophages/immunology Mice Mice, Inbred NOD Mice, Transgenic Models, Biological T-Lymphocytes/immunology
Chemicals
Glutamate Decarboxylase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Cooke A
Department of Pathology, Cambridge University, UK.
Article Info
Journal
Current biology : CB
Abbr.
Curr Biol
ISSN
0960-9822
DOI
10.1016/s0960-9822(94)00038-2
Published
1994-02-01
Pages
158-60
Language
English
Region
England
NLM ID
9107782
Subset
IM
External Links
PubMed source DOI: 10.1016/s0960-9822(94)00038-2 View journal details
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