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PMID: 79297 Published · ppublish English Journal Article

Luxol-fast-blue-staining of nerve cell nucleoli as indicator for acidotic lesion in cases of intracranial hypertension?

Acta neuropathologica ·Vol. 42 ·No. 3 ·1978-06-30 ·Pages 243-6

Dahmen HG, Müller W

Abstract

The allochromatic behaviour of nerve cell nucleoli in the Luxol-fast-blue-method (blue nucleoli) in cases of raised brain pressure is probably due to a lactacidotic pH-shift basing on cerebral hypoxia. In 109 out of 134 cases with blue nucleoli signs of cerebral hypertension could be observed. The IEP of nerve cell nucleoli was determined in the nuclei pontis. Clinical and pathophysiological data were evaluated.

MeSH Terms
Acidosis/pathology Cell Nucleolus Cerebrovascular Circulation Humans Hypoxia/pathology Intracranial Pressure Pons/pathology Staining and Labeling
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Dahmen H G
Müller W
References (8)
8 references, click to expand
  1. Total brain ischaemia in dogs: cerebral physiological and metabolic changes after 15 minutes of circulatory arrest.
    Resuscitation. 1975;4(2):97-113 PMID: 750
  2. [Observations on the biochemical role of the nucleolus].
    Biochim Biophys Acta. 1954 Oct;15(2):263-7 PMID: 13208692
  3. Some chemical properties of isolated pea nucleoli.
    J Biophys Biochem Cytol. 1959 Aug;6(1):57-60 PMID: 13673047
  4. Copper phthalocyanins as phospholipid stains.
    J Pathol Bacteriol. 1955 Oct;70(2):554-7 PMID: 13295937
  5. Experimental cerebral oligemia and ischemia produced by intracranial hypertension. Part 1: Pathophysiology, electroencephalography, cerebral blood flow, blood-brain barrier, and neurological function.
    J Neurosurg. 1975 Sep;43(3):308-17 PMID: 1151466
  6. Global ischemia in dogs: intracranial pressures, brain blood flow and metabolism.
    Stroke. 1975 Jan-Feb;6(1):21-7 PMID: 1111179
  7. The appearance of regional variations in metabolism at a critical level of diffuse cerebral oligemia.
    J Neurochem. 1977 Jan;28(1):71-9 PMID: 188986
  8. A method for the combined staining of cells and fibers in the nervous system.
    J Neuropathol Exp Neurol. 1953 Oct;12(4):400-3 PMID: 13097193
Article Info
Journal
Acta neuropathologica
Abbr.
Acta Neuropathol
ISSN
0001-6322
Published
1978-06-30
Pages
243-6
Language
English
Region
Germany
NLM ID
0412041
Subset
IM
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