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PMID: 791273 Published · ppublish English Journal Article

Changes in the distribution of intramembranous particles in hen erythrocytes during cell fusion induced by the bivalent-cation ionophore A23187.

The Biochemical journal ·Vol. 158 ·No. 3 ·1976-09-15 ·Pages 651-3

Vos J, Ahkong QF, Botham GM, Quirk SJ, Lucy JA

Abstract

Incubation of hen erythrocytes with Ca2+ and the bivalent-cation ionophore A23187 induced slight cell fusion in 1 h at 37 degrees C, and extensive fusion during a subsequent 15 min at 47 degrees C. Redistributions of intramembranous particles were observed, possibly involving interactions between Ca2+ and phospholipids, which are discussed in relation to molecular mechanimss of cell fusion.

MeSH Terms
Animals Anti-Bacterial Agents/pharmacology Calcimycin/pharmacology Calcium/pharmacology Cell Fusion/drug effects Cell Membrane/drug effects,ultrastructure Chickens Erythrocytes/drug effects,ultrastructure In Vitro Techniques Ionophores Microscopy, Electron Temperature Time Factors
Chemicals
Anti-Bacterial Agents Ionophores Calcimycin Calcium
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Vos J
Ahkong Q F
Botham G M
Quirk S J
Lucy J A
References (20)
20 references, click to expand
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Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj1580651
Published
1976-09-15
Pages
651-3
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1164023
Subset
IM
External Links
PubMed source DOI: 10.1042/bj1580651 PMC Full Text View journal details
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