Home LiteratureArticle Details
PMID: 7906398 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.

Nature ·Vol. 368 ·No. 6466 ·1994-03-03 ·Pages 32-8

Wilson R, Ainscough R, Anderson K, Baynes C, Berks M, Bonfield J, Burton J, Connell M, Copsey T, Cooper J

Abstract

As part of our effort to sequence the 100-megabase (Mb) genome of the nematode Caenorhabditis elegans, we have completed the nucleotide sequence of a contiguous 2,181,032 base pairs in the central gene cluster of chromosome III. Analysis of the finished sequence has indicated an average density of about one gene per five kilobases; comparison with the public sequence databases reveals similarities to previously known genes for about one gene in three. In addition, the genomic sequence contains several intriguing features, including putative gene duplications and a variety of other repeats with potential evolutionary implications.

MeSH Terms
Animals Caenorhabditis elegans/genetics Chromosome Mapping Databases, Factual Genes, Helminth Genes, Homeobox Molecular Sequence Data Multigene Family RNA, Transfer/genetics Repetitive Sequences, Nucleic Acid Sequence Analysis, DNA
Chemicals
RNA, Transfer
Authors & Affiliations
10 authors, click to expand affiliations / ORCID
Wilson R
Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110.
Ainscough R
Anderson K
Baynes C
Berks M
Bonfield J
Burton J
Connell M
Copsey T
Cooper J
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/368032a0
Published
1994-03-03
Pages
32-8
Language
English
Region
England
NLM ID
0410462
Subset
IM
Databases
GENBANK
U00025, U00026, U00031, U00032, U00033, U00034, U00035, U00036, U00037, U00038, U00040, U00041, U00042, U00043, U00044, U00045, U00046, U00047, U00048, U00049, U00050, U00051, U00052, U00053, U00054, U00055, U00056, U00057, U00058, U00063
Corrections
CommentIn
PMID: 8107876
External Links
PubMed source DOI: 10.1038/368032a0 View journal details
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