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PMID: 789913 Published · ppublish English Journal Article

Bacteriophage-specific DNA-binding proteins in P22-lysogenic and in P22-infected Salmonella typhimurium.

Journal of virology ·Vol. 20 ·No. 1 ·1976-10-00 ·Pages 334-8

Schumann W, Lindenblatt E, Bade EG

Abstract

Crude extracts of Salmonella typhimurium lysogenic for phages P22 or L contain proteins that specifically retain phage DNA on nitrocellulose filters. Three DNA-binding activities were found after infection with P22. One is P22 specific, accounts for the largest proportion of DNA-binding proteins, and corresponds most likely to the c2 repressor. An early transient binding activity measured with both P22 and L DNA was found to be directly related to the expression of genes c1 and c3. A third, late binding activity for P22 and L DNA is related to phage production.

MeSH Terms
DNA, Viral/metabolism Filtration Genes, Regulator Lysogeny Mutation Protein Binding Salmonella Phages/metabolism Salmonella typhimurium/metabolism Viral Proteins/biosynthesis
Chemicals
DNA, Viral Viral Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Schumann W
Lindenblatt E
Bade E G
References (23)
23 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.20.1.334-338.1976
Published
1976-10-00
Pages
334-8
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC354995
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.20.1.334-338.1976 PMC Full Text View journal details
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