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PMID: 7877684 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Principles of CDK regulation.

Nature ·Vol. 374 ·No. 6518 ·1995-03-09 ·Pages 131-4

Morgan DO

Abstract

As key regulators of the cell cycle, the cyclin-dependent kinases must be tightly regulated by extra- and intracellular signals. The activity of cyclin-dependent kinases is controlled by four highly conserved biochemical mechanisms, forming a web of regulatory pathways unmatched in its elegance and intricacy.

MeSH Terms

Animals Catalysis Cell Cycle/physiology Cyclin-Dependent Kinases/antagonists & inhibitors,metabolism Cyclins/metabolism Phosphorylation

Chemicals

Cyclins Cyclin-Dependent Kinases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Morgan D O

Department of Physiology, University of California, San Francisco 94143-0444.

Article Info

Journal

Nature

Abbr.

Nature

ISSN

0028-0836

DOI

10.1038/374131a0

Published

1995-03-09

Pages

131-4

Language

English

Region

England

NLM ID

0410462

Subset

External Links

PubMed source DOI: 10.1038/374131a0 View journal details

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Principles of CDK regulation.

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