Home LiteratureArticle Details
PMID: 7831287 Published · ppublish English Journal Article

Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen.

Hill A, Ploegh H

Abstract

暂无摘要

MeSH Terms
ATP-Binding Cassette Transporters/metabolism Animals Antigen Presentation/immunology Antigens, Viral/immunology,metabolism Biological Transport Endoplasmic Reticulum/metabolism Humans Peptides/immunology,metabolism Rats
Chemicals
ATP-Binding Cassette Transporters Antigens, Viral Peptides
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hill A
Center for Cancer Research, Massachusetts Institute of Technology, Cambridge 02139-4307.
Ploegh H
References (42)
42 references, click to expand
  1. Assembly and function of the two ABC transporter proteins encoded in the human major histocompatibility complex.
    Nature. 1992 Feb 13;355(6361):641-4 PMID: 1538751
  2. Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling.
    J Exp Med. 1994 Nov 1;180(5):1591-7 PMID: 7964447
  3. Allelic variants of the human putative peptide transporter involved in antigen processing.
    Proc Natl Acad Sci U S A. 1992 May 1;89(9):3932-6 PMID: 1570316
  4. Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide.
    J Exp Med. 1992 Jun 1;175(6):1653-61 PMID: 1588286
  5. Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment.
    J Exp Med. 1992 Sep 1;176(3):729-38 PMID: 1324970
  6. Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter.
    Science. 1993 Aug 6;261(5122):769-71 PMID: 8342042
  7. Tumor rejection antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation.
    EMBO J. 1993 Aug;12(8):3143-51 PMID: 8344253
  8. TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective.
    Cell. 1993 Aug 13;74(3):577-84 PMID: 8348620
  9. Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains.
    J Immunol. 1993 Nov 1;151(9):4455-64 PMID: 8409412
  10. Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner.
    Proc Natl Acad Sci U S A. 1993 Oct 1;90(19):9130-4 PMID: 8415666
  11. Peptide translocation by variants of the transporter associated with antigen processing.
    Science. 1993 Dec 24;262(5142):2059-63 PMID: 8266106
  12. Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas.
    J Exp Med. 1994 Jan 1;179(1):335-40 PMID: 8270878
  13. Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator.
    J Exp Med. 1994 Feb 1;179(2):533-40 PMID: 8294864
  14. Selectivity of MHC-encoded peptide transporters from human, mouse and rat.
    Nature. 1994 Feb 17;367(6464):648-51 PMID: 8107849
  15. HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2.
    J Immunol. 1994 Mar 15;152(6):2736-41 PMID: 8144880
  16. Human cytomegalovirus-infected cells have unstable assembly of major histocompatibility complex class I complexes and are resistant to lysis by cytotoxic T lymphocytes.
    J Virol. 1994 May;68(5):2822-9 PMID: 8151753
  17. MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding.
    Nature. 1994 Apr 28;368(6474):864-7 PMID: 8159247
  18. Peptide size selection by the major histocompatibility complex-encoded peptide transporter.
    J Exp Med. 1994 May 1;179(5):1613-23 PMID: 8163941
  19. A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes.
    Cell. 1994 May 20;77(4):525-35 PMID: 8187174
  20. Interaction of MHC class I molecules with the transporter associated with antigen processing.
    Science. 1994 May 27;264(5163):1322-6 PMID: 8191286
  21. Association of class I major histocompatibility heavy and light chains induced by viral peptides.
    Nature. 1989 Aug 10;340(6233):443-8 PMID: 2666863
  22. Antigen recognition by class I-restricted T lymphocytes.
    Annu Rev Immunol. 1989;7:601-24 PMID: 2469442
  23. An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide.
    J Exp Med. 1994 Dec 1;180(6):2163-71 PMID: 7964491
  24. Characteristics of peptide and major histocompatibility complex class I/beta 2-microglobulin binding to the transporters associated with antigen processing (TAP1 and TAP2).
    Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):12716-20 PMID: 7809108
  25. Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD/Lt) haplotype translocate similar sets of peptides.
    Proc Natl Acad Sci U S A. 1994 Dec 20;91(26):13004-8 PMID: 7809164
  26. Human transporters associated with antigen processing possess a promiscuous peptide-binding site.
    Immunity. 1994 Apr;1(1):7-14 PMID: 7889401
  27. A sequential model for peptide binding and transport by the transporters associated with antigen processing.
    Immunity. 1994 Sep;1(6):491-500 PMID: 7895159
  28. A trans-acting major histocompatibility complex-linked gene whose alleles determine gain and loss changes in the antigenic structure of a classical class I molecule.
    J Exp Med. 1989 Sep 1;170(3):777-95 PMID: 2475574
  29. Defective presentation of endogenous antigen by a cell line expressing class I molecules.
    Science. 1990 Apr 20;248(4953):367-70 PMID: 2326647
  30. Presentation of viral antigen controlled by a gene in the major histocompatibility complex.
    Nature. 1990 May 31;345(6274):449-52 PMID: 2342577
  31. Assembly of MHC class I molecules analyzed in vitro.
    Cell. 1990 Jul 27;62(2):285-95 PMID: 2196996
  32. Reconstitution by MHC-restricted peptides of HLA-A2 heavy chain with beta 2-microglobulin, in vitro.
    Nature. 1991 Apr 18;350(6319):619-22 PMID: 2017257
  33. Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter.
    Nature. 1991 May 23;351(6324):323-4 PMID: 2034277
  34. Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter.
    Nature. 1991 Dec 19-26;354(6354):528-31 PMID: 1758495
  35. Polymorphism in a second ABC transporter gene located within the class II region of the human major histocompatibility complex.
    Proc Natl Acad Sci U S A. 1992 Feb 15;89(4):1463-7 PMID: 1741401
  36. Calnexin: a membrane-bound chaperone of the endoplasmic reticulum.
    Trends Biochem Sci. 1994 Mar;19(3):124-8 PMID: 8203019
  37. Genes required for cytotoxicity against virus-infected target cells in K and D regions of H-2 complex.
    Nature. 1975 Mar 20;254(5497):269-70 PMID: 1078719
  38. MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness.
    Adv Immunol. 1979;27:51-177 PMID: 92183
  39. Cytotoxic T cell recognition of the influenza nucleoprotein and hemagglutinin expressed in transfected mouse L cells.
    Cell. 1984 Nov;39(1):13-25 PMID: 6091906
  40. Cytotoxic T cells recognize fragments of the influenza nucleoprotein.
    Cell. 1985 Sep;42(2):457-67 PMID: 2411422
  41. Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance.
    Cell. 1985 Nov;43(1):215-22 PMID: 2934137
  42. Ham-2 corrects the class I antigen-processing defect in RMA-S cells.
    Nature. 1992 Feb 13;355(6361):647-9 PMID: 1538753
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1995-01-17
Pages
341-3
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC42735
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com