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PMID: 7827321 Published · ppublish English Journal Article

Sodium/calcium exchanger in olfactory receptor neurones of Xenopus laevis.

Neuroreport ·Vol. 5 ·No. 14 ·1994-09-08 ·Pages 1741-4

Jung A, Lischka FW, Engel J, Schild D

Abstract

Ca2+ ions enter neurones through various types of calcium and cation channels. The mechanisms by which Ca2+ ions are spatially buffered and expelled from neurones have been studied considerable less. Using calcium imaging in conjunction with the patch clamp technique, we investigated the Na/Ca exchanger in olfactory neurones and found evidence for its localization on the dendrite. It is suggested that this tends to decouple increases in [Ca2+]i occurring in the transduction compartments of the cell from processes in the soma.

MeSH Terms
Animals Calcium/metabolism Carrier Proteins/metabolism Choline/pharmacology Microscopy, Fluorescence Neurons, Afferent/drug effects,metabolism Olfactory Mucosa/cytology Patch-Clamp Techniques Photoreceptor Cells/physiology Receptors, Odorant/drug effects,metabolism Sodium/metabolism Sodium-Calcium Exchanger Xenopus laevis
Chemicals
Carrier Proteins Receptors, Odorant Sodium-Calcium Exchanger Sodium Choline Calcium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Jung A
Physiologisches Institut, Universität Göttingen, Germany.
Lischka F W
Engel J
Schild D
Article Info
Journal
Neuroreport
Abbr.
Neuroreport
ISSN
0959-4965
Published
1994-09-08
Pages
1741-4
Language
English
Region
England
NLM ID
9100935
Subset
IM
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