Home LiteratureArticle Details
PMID: 7822407 Published · ppublish English Comment Journal Article Research Support, Non-U.S. Gov't Review

A new role for motor proteins as couplers to depolymerizing microtubules.

The Journal of cell biology ·Vol. 128 ·No. 1-2 ·1995-01-00 ·Pages 1-4

Desai A, Mitchison TJ

Abstract

暂无摘要

MeSH Terms
Animals Chromosomal Proteins, Non-Histone/physiology Chromosomes/physiology Kinetochores/physiology Macromolecular Substances Microtubule Proteins/physiology Microtubules/physiology Models, Biological
Chemicals
Chromosomal Proteins, Non-Histone Macromolecular Substances Microtubule Proteins centromere protein E
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Desai A
Department of Biochemistry and Biophysics, University of California at San Francisco 94143.
Mitchison T J
References (20)
20 references, click to expand
  1. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis.
    J Cell Biol. 1995 Jan;128(1-2):95-104 PMID: 7822426
  2. Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro.
    J Cell Biol. 1995 Jan;128(1-2):107-15 PMID: 7822408
  3. Cell motility by labile association of molecules. The nature of mitotic spindle fibers and their role in chromosome movement.
    J Gen Physiol. 1967 Jul;50(6):Suppl:259-92 PMID: 6058222
  4. Assembly of microtubules onto kinetochores of isolated mitotic chromosomes of HeLa cells.
    Proc Natl Acad Sci U S A. 1975 Oct;72(10):4023-7 PMID: 1060085
  5. Theoretical problems related to the attachment of microtubules to kinetochores.
    Proc Natl Acad Sci U S A. 1985 Jul;82(13):4404-8 PMID: 3859869
  6. Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding.
    J Cell Biol. 1985 Sep;101(3):755-65 PMID: 4030893
  7. Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation.
    J Cell Biol. 1985 Sep;101(3):766-77 PMID: 4030894
  8. Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.
    J Cell Biol. 1987 Jan;104(1):9-18 PMID: 3793763
  9. On the mechanism of anaphase A: evidence that ATP is needed for microtubule disassembly and not generation of polewards force.
    J Cell Biol. 1987 Oct;105(4):1691-705 PMID: 3312236
  10. Polewards chromosome movement driven by microtubule depolymerization in vitro.
    Nature. 1988 Feb 11;331(6156):499-504 PMID: 3340202
  11. One-dimensional diffusion of microtubules bound to flagellar dynein.
    Cell. 1989 Dec 1;59(5):915-25 PMID: 2531633
  12. Cytoplasmic dynein is localized to kinetochores during mitosis.
    Nature. 1990 May 17;345(6272):263-5 PMID: 2139717
  13. Microtubule depolymerization promotes particle and chromosome movement in vitro.
    J Cell Biol. 1991 Mar;112(6):1165-75 PMID: 1999468
  14. Two different microtubule-based motor activities with opposite polarities in kinetochores.
    Nature. 1991 May 16;351(6323):206-11 PMID: 2041567
  15. Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis.
    J Cell Biol. 1992 Nov;119(3):569-82 PMID: 1400593
  16. CENP-E is a putative kinetochore motor that accumulates just before mitosis.
    Nature. 1992 Oct 8;359(6395):536-9 PMID: 1406971
  17. Microtubule-associated motility in cytoplasmic extracts of sea urchin eggs.
    Cell Motil Cytoskeleton. 1993;24(3):167-78 PMID: 8467524
  18. Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism.
    J Cell Biol. 1993 Aug;122(4):859-75 PMID: 8349735
  19. In vitro motility assays using microtubules tethered to Tetrahymena pellicles.
    Methods Cell Biol. 1993;39:149-65 PMID: 8246795
  20. KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore.
    Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7212-6 PMID: 8041770
Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.128.1.1
Published
1995-01-00
Pages
1-4
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2120340
Subset
IM
Corrections
CommentOn
PMID: 7822408
CommentOn
PMID: 7822426
External Links
PubMed source DOI: 10.1083/jcb.128.1.1 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2