Expression of the plasmid pKM101--determined DNA repair system in recA- and lex- strains of Escherichia coli.

Molecular & general genetics : MGG ·Vol. 145 ·No. 3 ·1976-06-15 ·Pages 303-6

Monti-Bragadin C, Babudri N, Samer L

Abstract

pKM101, a plasmid R factor of the N compatibility group increases methylmethane sulfonate mutagenesis and diminishes UV-killing in recA+ LEX+ and recA+ lex- strains, , but not in recA-lex+ strains. The induction of a "reclex" dependent colicin is not present in lex- strains carrying the pKM101 factor. These facts indicate that pKM101 acts through an error-prone DNA repair system which is recA+ dependent, but not lex+ dependent.

MeSH Terms

Conjugation, Genetic DNA Repair Drug Resistance, Microbial Escherichia coli/metabolism Extrachromosomal Inheritance Mutation Plasmids Recombination, Genetic Salmonella typhimurium/metabolism Streptomycin/pharmacology Tetracycline/pharmacology Tryptophan/metabolism

Chemicals

Tryptophan Tetracycline Streptomycin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Monti-Bragadin C

Babudri N

Samer L

References (14)

14 references, click to expand

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Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF00325827

Published

1976-06-15

Pages

303-6

Language

English

Region

Germany

NLM ID

0125036

Subset

External Links

PubMed source DOI: 10.1007/BF00325827

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Expression of the plasmid pKM101--determined DNA repair system in recA- and lex- strains of Escherichia coli.

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