Regulated secretion. Helper proteins for neuroendocrine secretion.

Current biology : CB ·Vol. 5 ·No. 3 ·1995-03-01 ·Pages 242-5

Huttner WB, Natori S

Abstract

The granins, known to be general constituents of neuroendocrine secretory granules, are regulators of the proteolytic processing of peptide precursors and promote their aggregation-mediated sorting into secretory granules.

MeSH Terms

Animals Cell Line Chromogranins/physiology Cytoplasmic Granules/physiology,ultrastructure Endopeptidases/metabolism Enzyme Activation Models, Biological Neurosecretory Systems/physiology,ultrastructure Proprotein Convertase 2 Protein Processing, Post-Translational Proteins/physiology Subtilisins/metabolism

Chemicals

Chromogranins Proteins Endopeptidases Subtilisins Proprotein Convertase 2

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Huttner W B

Department of Neurobiology, University of Heidelberg, Germany.

Natori S

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(95)00049-2

Published

1995-03-01

Pages

242-5

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(95)00049-2 View journal details

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