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PMID: 7763952 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Protein-based artificial retinas.

Trends in biotechnology ·Vol. 11 ·No. 7 ·1993-07-00 ·Pages 292-300

Chen Z, Birge RR

Abstract

Artificial retinas based on the light transducing photoelectric protein bacteriorhodopsin exhibit differential responsivity, edge enhancement and motion detection. Under appropriate conditions, these artificial receptors mimic the differential responsivity characteristic of mammalian photoreceptor cells. The use of orientated bacteriorhodopsin to generate the photoelectrical signal provides rapid responsivity, high quantum efficiency and offers the potential of directly coupling the protein response to charge-sensitive semiconductor arrays. The ability to manipulate the properties of the protein via chemical and genetic methods enhances design flexibility.

MeSH Terms
Animals Artificial Organs Bacteriorhodopsins/chemistry,physiology,radiation effects Biotechnology Evaluation Studies as Topic Humans Models, Molecular Photochemistry Retina/physiology
Chemicals
Bacteriorhodopsins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Chen Z
W. M. Keck Center for Molecular Electronics, Syracuse University, NY 13244-4100.
Birge R R
Article Info
Journal
Trends in biotechnology
Abbr.
Trends Biotechnol
ISSN
0167-7799
Published
1993-07-00
Pages
292-300
Language
English
Region
England
NLM ID
8310903
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