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PMID: 7704521 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review

Production and structure of diabodies.

Structure (London, England : 1993) ·Vol. 2 ·No. 12 ·1994-12-15 ·Pages 1121-3

Poljak RJ

Abstract

The first crystal structure of a diabody, a bivalent antibody fragment, confirms previous predicted structures and techniques for generating bispecific bivalent antibody fragments of considerable therapeutic potential.

MeSH Terms

Amino Acid Sequence Binding Sites, Antibody Hybridomas Immunoglobulin Fragments/biosynthesis,chemistry,immunology Immunoglobulin Variable Region Molecular Sequence Data Protein Conformation

Chemicals

Immunoglobulin Fragments Immunoglobulin Variable Region

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Poljak R J

Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville 20850.

Article Info

Journal

Structure (London, England : 1993)

Abbr.

Structure

ISSN

0969-2126

DOI

10.1016/s0969-2126(94)00113-8

Published

1994-12-15

Pages

1121-3

Language

English

Region

United States

NLM ID

101087697

Subset

External Links

PubMed source DOI: 10.1016/s0969-2126(94)00113-8 View journal details

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Production and structure of diabodies.

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