Tumor suppression. Lessons in p16 from phylum Falconium.

Current biology : CB ·Vol. 5 ·No. 1 ·1995-01-01 ·Pages 28-31

Sheaff RJ, Roberts JM

Abstract

Increasingly, biochemical and genetic evidence indicates that mutations in the gene encoding p16, an inhibitor of cyclin-dependent kinases, may play a role in some forms of hereditary and sporadic tumors.

MeSH Terms

Animals Carrier Proteins/genetics,physiology Cell Cycle Cyclin-Dependent Kinase Inhibitor p16 Cyclin-Dependent Kinases/antagonists & inhibitors Genes, Retinoblastoma Genes, Tumor Suppressor Humans Mutation Neoplasms/genetics

Chemicals

Carrier Proteins Cyclin-Dependent Kinase Inhibitor p16 Cyclin-Dependent Kinases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sheaff R J

Department of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98104.

Roberts J M

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(95)00009-1

Published

1995-01-01

Pages

28-31

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(95)00009-1 View journal details

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Tumor suppression. Lessons in p16 from phylum Falconium.

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