Home LiteratureArticle Details
PMID: 769674 Published · ppublish English Journal Article

Antibiotic resistance and Hly plasmids in serotypes of Escherichia coli associated with porcine enteric disease.

Antimicrobial agents and chemotherapy ·Vol. 9 ·No. 1 ·1976-01-00 ·Pages 6-10

Jorgensen ST, Poulsen AL

Abstract

A total of 359 hemolytic Escherichia coli strains, representing eight pig pathogenic serotypes and isolated from pigs with enteric disease, was tested for transferable resistance to eight antibiotics. The co-transfer of plasmids controlling hemolysin production (Hly) with antibiotic resistance plasmids (R-factors) was evaluated. Transferable resistance to tetracycline, streptomycin, and/or sulfonamides was found in 47% of the total number of strains and 80% of the resistant ones. Chloramphenicol resistance was seldom seen. Co-transfer of Hly with R-factors occurred in 22.5% of the strains, generally to a degree excluding a genetic linkage. Stable coexistence of two R-factors in a cell was indicated by transfer patterns in 29 of the strains.

MeSH Terms
Animals Anti-Bacterial Agents/pharmacology Conjugation, Genetic Culture Media Drug Resistance, Microbial Escherichia coli/immunology Extrachromosomal Inheritance Plasmids R Factors Serotyping Swine Swine Diseases/microbiology
Chemicals
Anti-Bacterial Agents Culture Media
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Jorgensen S T
Poulsen A L
References (20)
20 references, click to expand
  1. Cellophane transfer: application to the study of activity of combinations of antibiotics.
    Appl Microbiol. 1960 Jul;8:193-9 PMID: 13808981
  2. Infective heredity of multiple drug resistance in bacteria.
    Bacteriol Rev. 1963 Mar;27:87-115 PMID: 13999115
  3. Replica plating and indirect selection of bacterial mutants.
    J Bacteriol. 1952 Mar;63(3):399-406 PMID: 14927572
  4. Transfer factors in Escherichia coli with particular regard to their incidence in enteropathogenic strains.
    J Gen Microbiol. 1970 Aug;62(3):287-99 PMID: 4924620
  5. A proposal for a uniform nomenclature in bacterial genetics.
    Genetics. 1966 Jul;54(1):61-76 PMID: 5961488
  6. Anti-microbial drugs in animal feeds.
    Nature. 1968 May 25;218(5143):728-31 PMID: 4297419
  7. [Plasmid determinants of the atypical "lactose positive" character in "S. typhi-murium" and "S. oranienburg" isolates from epidemic in Brasil, 1971-1973 (author's transl)].
    Ann Microbiol (Paris). 1974 Apr;125A(3):261-85 PMID: 4609114
  8. Incompatibility reactions of R plasmids isolated from Escherichia coli of animal origin.
    J Bacteriol. 1974 Oct;120(1):185-90 PMID: 4608595
  9. [Occurrence and distribution of drug resistant Escherichia coli in feces from cattle and swine].
    Nord Vet Med. 1972 Dec;24(12):651-9 PMID: 4580598
  10. Incidence of drug resistance and transmissible R factors in strains of E. coli isolated from faeces of healthy pigs.
    Acta Vet Scand. 1973;14(3):381-91 PMID: 4586123
  11. Occurrence and transfer of antibiotic resistance, colicinogeny and haemolysin production in Escherichia coli strains isolated from cases of colibacillosis.
    Acta Microbiol Pol A. 1974;6(2):155-62 PMID: 4600128
  12. Enteric Escherichia coli diseases in weaned pigs.
    Nord Vet Med. 1974 Mar;26(3):226-38 PMID: 4598277
  13. Haemolytic Escherichia coli associated with enteritis and enterotoxaemia in pigs in Denmark, with particular reference to the rapid spread of serogroup 0149:K91.
    Nord Vet Med. 1974 Mar;26(3):219-25 PMID: 4598276
  14. Distribution of transferable drug-resistance factors in fecal Escherichia coli from healthy pigs.
    Natl Inst Anim Health Q (Tokyo). 1972 Spring;12(1):17-22 PMID: 4557614
  15. Prevalence of extrachromosomal drug resistance. Bacterial drug resistance in animals.
    Ann N Y Acad Sci. 1971 Jun 11;182:40-51 PMID: 4941828
  16. Observations on the pathogenic properties of the K88, Hly and Ent plasmids of Escherichia coli with particular reference to porcine diarrhoea.
    J Med Microbiol. 1971 Nov;4(4):467-85 PMID: 4944321
  17. Transferable drug resistance among Enterobacteriaceae isolated from cases of neonatal diarrhea in calves and piglets.
    Appl Microbiol. 1969 Dec;18(6):961-4 PMID: 4905699
  18. The relationship between different transmissible plasmids introduced by F into the same strain of Escherichia coli K12.
    J Gen Microbiol. 1970 Aug;62(3):227-85 PMID: 4924619
  19. The transmissible nature of the genetic factor in Escherichia coli that controls haemolysin production.
    J Gen Microbiol. 1967 Apr;47(1):153-61 PMID: 5340526
  20. Characterization of a transfer factor associated with drug resistance in Salmonella typhimurium.
    Nature. 1965 Nov 27;208(5013):843-9 PMID: 5331112
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.9.1.6
Published
1976-01-00
Pages
6-10
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC429466
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.9.1.6 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2