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PMID: 766895 Published · ppublish English Clinical Trial Controlled Clinical Trial Historical Article Journal Article

Cardiovascular effects of insulin.

British medical journal ·Vol. 1 ·No. 6007 ·1976-02-21 ·Pages 430-2

Page MM, Smith RB, Watkins PJ

Abstract

Insulin increased the heart rates of seven diabetics with normal cardiovascular reflexes. This effect, which was not due to hypoglycaemia, was greater in the upright than in the supine position and was produced by as little as one unit given intravenously. This increase in heart rate may be a compensatory response to maintain cardiac output.

MeSH Terms
Blood Glucose/analysis Clinical Trials as Topic Diabetes Mellitus/blood,physiopathology Heart Rate/drug effects History, 15th Century History, 16th Century Humans Insulin/pharmacology Male Posture Time Factors
Chemicals
Blood Glucose Insulin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Page M M
Smith R B
Watkins P J
References (4)
4 references, click to expand
  1. The role of adrenaline in hypoglycaemic reactions in man.
    Clin Sci (Lond). 1955 Nov;14(4):639-51 PMID: 13270448
  2. HEART RATE RESPONSE TO THE VALSALVA MANEUVER AS A TEST OF CIRCULATORY INTEGRITY.
    JAMA. 1963 Oct 19;186:200-5 PMID: 14057108
  3. Letter: Cardioactive substances leached from a commercial hemodialysis set.
    N Engl J Med. 1975 Jun 19;292(25):1356 PMID: 1128619
  4. The effect of intravenous insulin on the circulatory responses to tilting in normal and diabetic subjects with special reference to baroceptor reflex block and atypical hypoglycaemic reactions.
    Clin Sci. 1968 Jun;34(3):419-30 PMID: 5666872
Article Info
Journal
British medical journal
Abbr.
Br Med J
ISSN
0007-1447
Published
1976-02-21
Pages
430-2
Language
English
Region
England
NLM ID
0372673
PMCID
PMC1638991
Subset
IM
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