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PMID: 7648032 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

A TH1-TH2-like switch in candidiasis: new perspectives for therapy.

Trends in microbiology ·Vol. 3 ·No. 6 ·1995-06-00 ·Pages 237-40

Puccetti P, Romani L, Bistoni F

Abstract

An imbalance in TH1-type and TH2-type responses may allow Candida albicans to modify the host response to favor its own persistence. This hypothesis has important consequences for allergy, autoimmunity and co-infection, and also highlights a potential role for cytokine and anti-cytokine therapy in Candida-related pathology.

MeSH Terms
Animals Candida albicans/immunology Candidiasis/drug therapy,immunology Cytokines/antagonists & inhibitors,immunology,therapeutic use Humans Immune Tolerance Th1 Cells/immunology Th2 Cells/immunology
Chemicals
Cytokines
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Puccetti P
Dept of Experimental Medicine, University of Rome Tor Vergata, Italy.
Romani L
Bistoni F
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
DOI
10.1016/s0966-842x(00)88931-3
Published
1995-06-00
Pages
237-40
Language
English
Region
England
NLM ID
9310916
Subset
IM
External Links
PubMed source DOI: 10.1016/s0966-842x(00)88931-3 View journal details
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