Cell-cycle checkpoints. Keeping mitosis in check.

Current biology : CB ·Vol. 5 ·No. 4 ·1995-04-01 ·Pages 376-9

Humphrey T, Enoch T

Abstract

Mutations in an essential yeast gene, encoding DNA polymerase epsilon, abolish the dependence of mitosis on the completion of DNA replication, suggesting that the replication complex provides the checkpoint signal.

Related Genes

DUN

MeSH Terms

Animals DNA Polymerase II DNA Replication/physiology DNA-Directed DNA Polymerase/genetics,metabolism Humans Mitosis/physiology Mutation Saccharomyces cerevisiae/genetics,physiology Schizosaccharomyces/genetics,physiology

Chemicals

DNA Polymerase II DNA-Directed DNA Polymerase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Humphrey T

Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Enoch T

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(95)00077-7

Published

1995-04-01

Pages

376-9

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(95)00077-7 View journal details

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