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PMID: 7613085 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Chromatin-mediated transcriptional repression in yeast.

Current opinion in genetics & development ·Vol. 5 ·No. 2 ·1995-04-00 ·Pages 168-73

Roth SY

Abstract

Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.

Related Genes

Ssn6 Tup1

MeSH Terms

Chromatin/physiology Gene Expression Regulation, Fungal Saccharomyces cerevisiae/genetics Transcription, Genetic

Chemicals

Chromatin

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Roth S Y

Department of Biochemistry and Molecular Biology, University of Texas, MD Anderson Cancer Center, Houston 77005, USA.

Article Info

Journal

Current opinion in genetics & development

Abbr.

Curr Opin Genet Dev

ISSN

0959-437X

DOI

10.1016/0959-437x(95)80004-2

Published

1995-04-00

Pages

168-73

Language

English

Region

England

NLM ID

9111375

Subset

External Links

PubMed source DOI: 10.1016/0959-437x(95)80004-2 View journal details

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