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PMID: 7590342 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

The rhodopsin-encoding gene of bony fish lacks introns.

Gene ·Vol. 164 ·No. 2 ·1995-10-27 ·Pages 273-7

Fitzgibbon J, Hope A, Slobodyanyuk SJ, Bellingham J, Bowmaker JK, Hunt DM

Abstract

A study of the sequences of the rhodopsin-encoding genes (Rh) in eight fish species from two of the major subdivisions of the teleosts reveals that no introns are present in the coding region. This contrasts with the opsin-encoding genes of all other vertebrates where either four or five introns are invariably found. Phylogenetic analysis shows that this intronless teleost Rh is homologous to the intron-containing Rh of amphibia, birds and mammals. Possible mechanisms for intron loss are discussed, including replacement by homologous conversion of Rh with a processed cDNA.

MeSH Terms

Amphibians/genetics Anguilla/genetics Animals Base Sequence Birds/genetics Cattle Chickens DNA Primers Decapodiformes/genetics Drosophila/genetics Fishes/genetics Genetic Variation Goldfish/genetics Humans Introns Mammals/genetics Mice Molecular Sequence Data Phylogeny Polymerase Chain Reaction Rhodopsin/genetics Sequence Homology, Nucleic Acid Species Specificity Vertebrates/genetics Xenopus/genetics

Chemicals

DNA Primers Rhodopsin

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Fitzgibbon J

Department of Molecular Genetics, Institute of Ophthalmology, University of London, UK.

Hope A

Slobodyanyuk S J

Bellingham J

Bowmaker J K

Hunt D M

Article Info

Journal

Gene

Abbr.

Gene

ISSN

0378-1119

DOI

10.1016/0378-1119(95)00458-i

Published

1995-10-27

Pages

273-7

Language

English

Region

Netherlands

NLM ID

7706761

Subset

Databases

GENBANK

L42953, L42954

External Links

PubMed source DOI: 10.1016/0378-1119(95)00458-i View journal details

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The rhodopsin-encoding gene of bony fish lacks introns.

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