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PMID: 7529436 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S. Review

Aquaporins: water channel proteins of plant and animal cells.

Trends in biochemical sciences ·Vol. 19 ·No. 10 ·1994-10-00 ·Pages 421-5

Chrispeels MJ, Agre P

Abstract

Certain biological membranes, such as the erythrocyte plasma membrane, have a high osmotic water permeability, and such membranes have long been suspected of harboring water channels. The molecular identity of these channels has now been established with the purification of water-channel proteins and the cloning of the genes encoding them. Homologous water-channel proteins, called 'aquaporins', are present in plants and animals. These channels are water selective and do not allow ions or metabolites to pass through them. Their discovery is providing new insights into how plant and animal cells facilitate and regulate the passage of water through their membranes.

MeSH Terms
Animals Arabidopsis Cell Membrane/chemistry Cell Membrane Permeability Female Ion Channels/genetics,metabolism,physiology Oocytes Plants Water/metabolism Xenopus laevis
Chemicals
Ion Channels Water
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Chrispeels M J
Department of Biology, University of California San Diego, La Jolla 92093-0116.
Agre P
Article Info
Journal
Trends in biochemical sciences
Abbr.
Trends Biochem Sci
ISSN
0968-0004
Published
1994-10-00
Pages
421-5
Language
English
Region
England
NLM ID
7610674
Subset
IM
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