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PMID: 7526792 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Multiple effects of interferon on the replication of human immunodeficiency virus type 1.

Antiviral research ·Vol. 24 ·No. 2-3 ·1994-07-00 ·Pages 205-19

Pitha PM

Abstract

In this review, I shall summarize the major findings about the effect of IFN on the replication of HIV-1 virus in model systems in vitro and will describe the known molecular mechanisms involved in the IFN-mediated inhibition of HIV-1 replication. Finally, I shall relate these findings to the unique features of the HIV-1 replication cycle.

MeSH Terms

HIV-1/drug effects,growth & development Humans Interferons/pharmacology Lentivirus/drug effects Macrophages/microbiology Proviruses T-Lymphocytes/microbiology Transcription, Genetic Virus Replication/drug effects

Chemicals

Interferons

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Pitha P M

Oncology Center, Johns Hopkins University, Baltimore, MD 21231.

Article Info

Journal

Antiviral research

Abbr.

Antiviral Res

ISSN

0166-3542

DOI

10.1016/0166-3542(94)90068-x

Published

1994-07-00

Pages

205-19

Language

English

Region

Netherlands

NLM ID

8109699

Subset

Grants

NIAID NIH HHS · AI 26123 · United States

External Links

PubMed source DOI: 10.1016/0166-3542(94)90068-x View journal details

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Multiple effects of interferon on the replication of human immunodeficiency virus type 1.

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