Home LiteratureArticle Details

PMID: 7518583 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Removal of t-butyldimethylsilyl protection in RNA-synthesis. Triethylamine trihydrofluoride (TEA, 3HF) is a more reliable alternative to tetrabutylammonium fluoride (TBAF).

Nucleic acids research ·Vol. 22 ·No. 12 ·1994-06-25 ·Pages 2430-1

Westman E, Strömberg R

Abstract

暂无摘要

MeSH Terms

Chromatography, High Pressure Liquid Ethylamines Indicators and Reagents Organosilicon Compounds Quaternary Ammonium Compounds RNA/chemical synthesis,chemistry

Chemicals

Ethylamines Indicators and Reagents Organosilicon Compounds Quaternary Ammonium Compounds t-butyldimethylsilyl compounds RNA tetrabutylammonium triethylamine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Westman E

Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, Sweden.

Strömberg R

References (4)

4 references, click to expand

Studies on the t-butyldimethylsilyl group as 2'-O-protection in oligoribonucleotide synthesis via the H-phosphonate approach.
Nucleic Acids Res. 1988 Oct 11;16(19):9285-98 PMID: 3174451
Evaluation of 2'-hydroxyl protection in RNA-synthesis using the H-phosphonate approach.
Nucleic Acids Res. 1994 Jan 11;22(1):94-9 PMID: 8127660
Effect of excess water on the desilylation of oligoribonucleotides using tetrabutylammonium fluoride.
Nucleic Acids Res. 1993 Oct 11;21(20):4739-41 PMID: 8233822
Chemical synthesis of a biologically active natural tRNA with its minor bases.
Nucleic Acids Res. 1992 Oct 11;20(19):5159-66 PMID: 1383941

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/22.12.2430

Published

1994-06-25

Pages

2430-1

Language

English

Region

England

NLM ID

0411011

PMCID

PMC523709

Subset

External Links

PubMed source DOI: 10.1093/nar/22.12.2430 PMC Full Text View journal details

Analysis Services

Removal of t-butyldimethylsilyl protection in RNA-synthesis. Triethylamine trihydrofluoride (TEA, 3HF) is a more reliable alternative to tetrabutylammonium fluoride (TBAF).

Contact

WeChat Official Account