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PMID: 7503937 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2.

Genomics ·Vol. 17 ·No. 3 ·1993-09-00 ·Pages 759-61

Fernández-Ruiz E, Armesilla AL, Sánchez-Madrid F, Vega MA

Abstract

The human CD36 is a member of a gene family of structurally related glycoproteins and functions as a receptor for collagen type I and thrombospondin. CD36 also binds to red blood cells infected with the human malaria parasite Plasmodium falciparum. In the present study, the CD36 gene was assigned to chromosome 7 by using the polymerase chain reaction with DNA from human-hamster somatic cell hybrids. Furthermore, the use of a CD36 genomic probe has allowed the localization of the CD36 locus to the 7q11.2 band by fluorescence in situ hybridization coupled with GTG-banding.

Related Genes
CD36
MeSH Terms
Amino Acid Sequence Animals Base Sequence CD36 Antigens Chromosome Mapping Chromosomes, Human, Pair 7 Collagen/metabolism Cricetinae DNA/genetics Humans Hybrid Cells In Situ Hybridization, Fluorescence Integrins/genetics Membrane Glycoproteins/metabolism Molecular Sequence Data Platelet Membrane Glycoproteins/genetics Polymerase Chain Reaction Receptors, Collagen Receptors, Cytoadhesin/genetics Receptors, Immunologic Receptors, Lipoprotein Receptors, Scavenger Thrombospondins
Chemicals
CD36 Antigens Integrins Membrane Glycoproteins Platelet Membrane Glycoproteins Receptors, Collagen Receptors, Cytoadhesin Receptors, Immunologic Receptors, Lipoprotein Receptors, Scavenger Thrombospondins Collagen DNA
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Fernández-Ruiz E
Departamento de Immunología, Hospital de la Princesa, Madrid, Spain.
Armesilla A L
Sánchez-Madrid F
Vega M A
Article Info
Journal
Genomics
Abbr.
Genomics
ISSN
0888-7543
DOI
10.1006/geno.1993.1401
Published
1993-09-00
Pages
759-61
Language
English
Region
United States
NLM ID
8800135
Subset
IM
External Links
PubMed source DOI: 10.1006/geno.1993.1401 View journal details
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