Stimulation by growth hormone of somatostatin release from the rat hypothalamus in vitro.

Clinical endocrinology ·Vol. 9 ·No. 6 ·1978-12-00 ·Pages 583-6

Sheppard MC, Kronheim S, Pimstone BL

Abstract

Growth hormone (GH) has been shown to cause a dose-dependent increase in the release of immunoreactive somatostatin from the rat hypothalamus in vitro, thus providing further evidence that GH may be involved in a "short loop" feedback, controlling its own secretion via hypothalamic somatostatin release.

MeSH Terms

Animals Growth Hormone/pharmacology Hypothalamus/drug effects,metabolism In Vitro Techniques Potassium Chloride/pharmacology Rats Somatostatin/metabolism Thyrotropin Veratrine/pharmacology

Chemicals

Somatostatin Potassium Chloride Thyrotropin Growth Hormone Veratrine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Sheppard M C

Kronheim S

Pimstone B L

Article Info

Journal

Clinical endocrinology

Abbr.

Clin Endocrinol (Oxf)

ISSN

0300-0664

DOI

10.1111/j.1365-2265.1978.tb01518.x

Published

1978-12-00

Pages

583-6

Language

English

Region

England

NLM ID

0346653

Subset

External Links

PubMed source DOI: 10.1111/j.1365-2265.1978.tb01518.x View journal details

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Stimulation by growth hormone of somatostatin release from the rat hypothalamus in vitro.

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