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LiteratureArticle Details
PMID: 7434017
Published · ppublish
English
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Silent nucleotide substitutions and the molecular evolutionary clock.
Abstract
Half of the nucleotide substitutions during the evolutionary divergence of genes in animals, bacteria, and viruses are silent changes. These result from an inherent biochemical property of DNA and are fixed by genetic drift. Evolution may be viewed as a device for protecting DNA molecules from extinction.
MeSH Terms
Animals
Base Sequence
Biological Evolution
Codon
DNA/genetics
DNA, Viral/genetics
Genes
Genetic Code
Globins/genetics
Histones/genetics
Mutation
RNA, Messenger/genetics
Chemicals
Codon
DNA, Viral
Histones
RNA, Messenger
Globins
DNA
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1980-11-28
Pages
973-8
Language
English
Region
United States
NLM ID
0404511
Subset
IM
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