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PMID: 742936 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

H-Y antigen in testes of XX(BALB)/XY (C3H) chimaeric male mouse.

Archives of andrology ·Vol. 1 ·No. 1 ·1978-00-00 ·Pages 103-9

Ohno S, Ciccarese S, Nagai Y, Wachtel SS

Abstract

Among experimentally produced BALB/C3H aggregation (Blastocyst fusion) chimaeras of the mouse, one fertile XX (BALB)/XY (C3H) male was identified who maintained 50% or more female cells in many parts of his body. Results of H-Y antibody absorption tests revealed an XY to XX transfer of testis-organizing H-Y antigen among testicular Sertoli and Leydig cells, but not among spleen and epidermal cells.

MeSH Terms

Animals Chimera Histocompatibility Antigens/analysis Immunogenetics Leydig Cells/immunology,ultrastructure Male Mice Mice, Inbred BALB C Mice, Inbred C3H Sertoli Cells/immunology,ultrastructure Sex Chromosomes Skin/immunology,ultrastructure Spleen/immunology,ultrastructure Testis/immunology,ultrastructure Y Chromosome/immunology

Chemicals

Histocompatibility Antigens

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Ohno S

Ciccarese S

Nagai Y

Wachtel S S

Article Info

Journal

Archives of andrology

Abbr.

Arch Androl

ISSN

0148-5016

DOI

10.3109/01485017808988325

Published

1978-00-00

Pages

103-9

Language

English

Region

England

NLM ID

7806755

Subset

External Links

PubMed source DOI: 10.3109/01485017808988325

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H-Y antigen in testes of XX(BALB)/XY (C3H) chimaeric male mouse.

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