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PMID: 7399699 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Microflora and chemical composition of dental plaque from subjects with hereditary fructose intolerance.

Infection and immunity ·Vol. 28 ·No. 3 ·1980-06-00 ·Pages 853-9

Hoover CI, Newbrun E, Mettraux G, Graf H

Abstract

We compared the microbiological and chemical composition of dental plaque from subjects with hereditary fructose intolerance who restrict their dietary sugar intake with that of control subjects who do not. The two groups showed no significant differences in chemical composition of plaque: the mean protein, carbohydrate, calcium, magnesium, and phosphate contents were similar. Dental plaque from both groups contained similar numbers of total colony-forming units per microgram of plaque protein, and Streptococcus sanguis, an indigenous nonpathogen, was isolated with equal frequency from plaque samples of both groups. However, potentially odontopathic Streptococcus mutans and Lactobacillus were isolated three to four times more frequently from plaque samples of control subjects than from plaque samples of subjects with hereditary fructose intolerance. Clearly, diet (sucrose in particular) influences the colonization and multiplication of specific cariogenic organisms in dental plaque.

MeSH Terms
Adolescent Adult Calcium/analysis Carbohydrate Metabolism, Inborn Errors/genetics Carbohydrates/analysis Child Dental Plaque/analysis,microbiology Female Fructose Intolerance/genetics Humans Lactobacillus/isolation & purification Magnesium/analysis Male Middle Aged Phosphates/analysis Proteins/analysis Streptococcus mutans/isolation & purification Streptococcus sanguis/isolation & purification
Chemicals
Carbohydrates Phosphates Proteins Magnesium Calcium
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hoover C I
Newbrun E
Mettraux G
Graf H
References (44)
44 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.28.3.853-859.1980
Published
1980-06-00
Pages
853-9
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC551029
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.28.3.853-859.1980 PMC Full Text View journal details
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